Disease Specific Cancer Panels

Colorectal Cancer:

  • KRAS & BRAF
  • Multiplex Solid Tumor panel, including KRAS, BRAF, PIK3CA and CTNNB1
  • Microsatellite instability
  • Mismatch Repair Protein Expression by IHC (for MLH1, MSH2, MSH6, PMS2)
  • Lynch Syndrome Sequencing panel (MLH1, MSH2, MSH6)

Non-Small Cell Lung Cancer:

  • EGFR
  • ALK translocation (FDA-approved FISH probe)
  • Multiplex Solid Tumor Panel, including KRAS, ERBB2/HER2, BRAF, PIK3CA, CTNNB1 and NTRK genes
  • ROS1 (FISH)
  • RET (FISH)

Malignant Melanoma:

  • BRAF
  • NRAS
  • cKIT
  • GNAQ & GNA11 (ocular melanoma)

GI Stromal Tumor (GIST):

  • cKIT with reflex to PDGFRA
  • BRAF (for wild-type GIST)

Breast Cancer

  • HER2 (FISH)
  • PTEN (IHC)
  • PIK3CA
  • AKT1

Gastric Cancer

  • HER2 (FISH)

Endometrial Cancer (Endometrioid type)

  • PIK3CA
  • PTEN (IHC)
  • Multiplex solid tumor panel, including PIK3CA, RAS genes, BRAF, CTNNB1

Gliomas

  • MGMT methylation
  • IDH1&IDH2

Bladder Cancer

  • FGFR3

Thymic Carcinoma

  • cKIT