Mass cytometry / Cytof®

Mass Cytometry or CyTOF is a single-cell proteomics technology enabling the interrogation of up to 44 cell surface and intra-cellular biomarkers simultaneously using whole blood, PBMCs and segregated tissues.

In contrast to flow cytometry, antibodies are labeled with heavy metal isotopes rather than fluorochromes with readout by time-of-flight mass spectrometry.    

This high resolution approach allows deeper phenotypic and functional profiling of cells from normal and diseased states unveiling new cell types and functions.

This high-resolution approach allows for prospective and retrospective, highly standardized and reproducible analysis of clinical samples, revealing:

• Immune cell activation and inhibition
• Predictive biomarkers for treatment stratification
• On treatment changes reflective of therapeutic engagement